Gender differences in the association between the uric acid to high-density lipoprotein cholesterol ratio and diabetes risk: a mediation analysis of c-reactive protein, triglycerides, and insulin resistance
This study demonstrates that the association between UHR and diabetes risk exhibits gender differences, with higher diabetes risk observed in women, while men show stronger mediation effects in insulin resistance, lipid metabolism, and inflammatory response.
Authors
- Ying Chang (ORCID: https://orcid.org/0000-0003-4016-6200)
- Yiqian Qu (ORCID: https://orcid.org/0000-0001-5304-8196)
- Caixia Zheng
- Lingyong Cao (ORCID: https://orcid.org/0000-0003-0943-9960)
- Zhan Li (ORCID: https://orcid.org/0000-0001-5664-3863)
- Jianming Yin
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12944-024-02404-6
- Citations
- 11
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 3.73
Funders
- National Natural Science Foundation of China
- Zhejiang Chinese Medical University
- Natural Science Foundation of Zhejiang Province