Genome-wide association studies unveil major genetic loci driving insecticide resistance in Anopheles funestus in four eco-geographical settings across Cameroon
Our study uncovered regional variations in insecticide resistance candidate variants, emphasizing the need for a streamlined DNA-based diagnostic assay for genomic surveillance across Africa. These findings will contribute to the development of tailored resistance management strategies crucial for addressing the dynamic challenges of malaria control in Cameroon.
Authors
- Charles S. Wondji (ORCID: https://orcid.org/0000-0003-0791-3673)
- Magellan Tchouakui (ORCID: https://orcid.org/0000-0002-1683-8057)
- Leon M. J. Mugenzi (ORCID: https://orcid.org/0000-0002-6857-9608)
- Jack Hearn (ORCID: https://orcid.org/0000-0003-3358-4949)
- Gadji Mahamat
- Onana Boyomo (ORCID: https://orcid.org/0000-0003-4702-7916)
- Murielle J. Wondji (ORCID: https://orcid.org/0000-0002-7101-8115)
- Jonas A. Kengne-Ouafo (ORCID: https://orcid.org/0000-0003-3516-8498)
Institutions
- Université de Yaoundé I (CM)
- Liverpool School of Tropical Medicine (GB)
- Scotland's Rural College (GB)
- Pan African Institute for Development (CM)
- Ministry of Scientific Research and Innovation (CM)
- Syngenta (Switzerland) (CH)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12864-024-11148-7
- Citations
- 3
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Bill and Melinda Gates Foundation
- Wellcome Trust