Association of early-life factors with biological age acceleration and the mediating effect of social environment risks in middle-aged and older adults
Our findings demonstrated a dose-dependent association of combined early-life risks with accelerated BA in middle-aged and older adults, partially mediated by social environment risks. The findings highlight the importance of early identification and surveillance of high-risk individuals for ageing acceleration during adulthood.
Authors
- Ming Jin (ORCID: https://orcid.org/0000-0003-3464-0623)
- Nan Li (ORCID: https://orcid.org/0000-0002-2932-9649)
- Ninghao Huang (ORCID: https://orcid.org/0000-0001-9001-784X)
- Ziyi Zhang (ORCID: https://orcid.org/0000-0002-2175-4931)
- Xiaojing Liu (ORCID: https://orcid.org/0009-0000-3637-0917)
- Zeping Yang (ORCID: https://orcid.org/0009-0004-2793-0678)
- Tao Huang (ORCID: https://orcid.org/0000-0001-5206-2471)
Institutions
- Peking University (CN)
- National Health and Family Planning Commission (CN)
Publication Details
- Journal
- Age and Ageing
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1093/ageing/afae272
- Citations
- 4
- Primary Topic
- Health disparities and outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.11
Funders
- Stroke Association
- NIHR Cambridge Biomedical Research Centre