The decrease in zinc‐finger E‐box‐binding homeobox‐1 could accelerate steroid‐induced osteonecrosis of the femoral head by repressing type‐H vessel formation via <i>Wnt/β‐catenin</i> pathway
The ZEB1 expression decreased in SONFH, causing a decrease in type-H vessel, and it mediated angiogenesis and osteogenesis by regulating the Wnt/β-catenin pathway, ultimately accelerating the process of SONFH.
Authors
- Xiaoqian Dang (ORCID: https://orcid.org/0000-0002-5498-6800)
- Guangyang Zhang (ORCID: https://orcid.org/0000-0001-6380-0468)
- Zhaopu Jing (ORCID: https://orcid.org/0000-0002-6027-2759)
- Yuanqing Cai (ORCID: https://orcid.org/0000-0001-5364-414X)
- Qingqing Song (ORCID: https://orcid.org/0000-0003-2111-5037)
- Leifeng Lv (ORCID: https://orcid.org/0000-0003-3297-2245)
- Jialin Liang (ORCID: https://orcid.org/0009-0003-9353-8722)
- Wang Wei (ORCID: https://orcid.org/0009-0008-3103-1180)
Institutions
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/ame2.12507
- Citations
- 1
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.48
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Central University Basic Research Fund of China