Maternal high-fat diet orchestrates offspring hepatic cholesterol metabolism via MEF2A hypermethylation-mediated CYP7A1 suppression
This study provides novel insights into how maternal HFD orchestrates hepatic cholesterol metabolism via MEF2A hypermethylation-mediated CYP7A1 suppression in offspring at weaning.
Authors
- Wenyu Zou (ORCID: https://orcid.org/0009-0000-6509-4990)
- Jia Zheng
- Ying Gao (ORCID: https://orcid.org/0000-0001-6972-3846)
- Honghua Wu (ORCID: https://orcid.org/0000-0002-5841-9248)
- Junqing Zhang (ORCID: https://orcid.org/0000-0002-8574-1945)
- Ling Zhang (ORCID: https://orcid.org/0000-0003-1155-4802)
- Shixuan Zhang (ORCID: https://orcid.org/0000-0001-6187-843X)
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s11658-024-00673-8
- Citations
- 12
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 13.31
Funders
- National Natural Science Foundation of China
- Beijing Nova Program