Ramelteon exposure and survival of critically Ill sepsis patients: a retrospective study from MIMIC-IV
This exploratory, retrospective study suggests an association between ramelteon exposure and reduced 30-day and 90-day mortality in septic patients compared with the non-exposure group. Considering the limitations of the retrospective design and the potential for unmeasured confounding, well-designed prospective studies and randomized controlled trials will be needed to confirm these findings.
Authors
- Ke‐Xuan Liu (ORCID: https://orcid.org/0000-0003-0221-366X)
- Yunyang Han (ORCID: https://orcid.org/0000-0001-5079-6826)
- Bing-Cheng Zhao (ORCID: https://orcid.org/0000-0002-5671-4999)
- Yu Tian (ORCID: https://orcid.org/0009-0009-6213-004X)
Institutions
- Nanfang Hospital (CN)
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Anesthesiology
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1186/s12871-024-02851-9
- Citations
- 2
- Primary Topic
- Hemodynamic Monitoring and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Beth Israel Deaconess Medical Center
- Massachusetts Institute of Technology
- Southern Medical University
- Nanfang Hospital