TiO<sub>2</sub>-Catalyzed Direct Diazenylation of Active Methylene Compounds with Diazonium Salts
Herein, we report a direct diazenylation of active methylene compounds that is environmentally friendly, cost-effective, and scalable, utilizing a heterogeneous TiO<sub>2</sub> catalyst that is both accessible and recyclable. The scope of this transformation shows excellent compatibility with both electron-rich and electron-poor diazonium salts, yielding the desired products in very good yields at room temperature.
Authors
- E. HAYASHI
- Iva S. de Jesus (ORCID: https://orcid.org/0000-0003-0254-3589)
- Luana da Silva Magalhães Forezi (ORCID: https://orcid.org/0000-0002-7657-4268)
- Rodolfo G. Fiorot (ORCID: https://orcid.org/0000-0002-4311-5989)
- Edson Gomes Evangelista (ORCID: https://orcid.org/0000-0002-2092-533X)
- Karine N. de Andrade (ORCID: https://orcid.org/0000-0002-7901-3183)
- Maria Antonieta Rodrigues
- Yuri P. V. de Carvalho
Institutions
- Universidade Federal Fluminense (BR)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1021/acs.joc.4c02266
- Citations
- 3
- Primary Topic
- Nanomaterials for catalytic reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.75
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro