Study on the Mechanism of UMI-77 in the Treatment of Sepsis-Induced Acute Lung Injury Based on Transcriptomics and Metabolomics
UMI-77 exerts its therapeutic effect in sepsis-induced ALI through intricate modulation of pivotal genes and metabolites, thereby influencing critical biological pathways. This study lays the groundwork for further development and clinical translation of UMI-77 as a potential therapeutic agent for sepsis-associated lung injuries.
Authors
- Yinghe Xu (ORCID: https://orcid.org/0000-0001-8863-7505)
- Jiaqi Zhu (ORCID: https://orcid.org/0000-0002-2142-7260)
- Hang Ni
- Cuicui Dong
- Jiatian Zhang
- Yubin Xu (ORCID: https://orcid.org/0000-0003-0340-4425)
- Zhiping Xia (ORCID: https://orcid.org/0000-0002-1273-5157)
Institutions
- Wenzhou Medical University (CN)
- Taizhou Central Hospital (CN)
- Zhejiang Taizhou Hospital (CN)
- Shaoxing People's Hospital (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/jir.s495512
- Citations
- 2
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.47