Oral ulcers as an early manifestation of histoplasmosis

Histoplasma capsulatum, the causative agent of histoplasmosis, is an uncommon systemic fungal illness that represents significant health risks to people living with HIV/AIDS (PLHV), especially those who are residents in endemic regions like Brazil. While oral histoplasmosis is rare, this observation can serve as a significant indicator of compromised immunological state, particularly in those with low numbers of TCD4+ cells. This study intends to examine recent literature on oral histoplasmosis and to provide a case of oral manifestations as the first indication of disseminated histoplasmosis in a young woman recently diagnosed with HIV.