Baihui‐Penetrating‐Qubin Acupuncture Attenuates Neurological Deficits Through SIRT1/FOXO1 Reducing Oxidative Stress and Neuronal Apoptosis in Intracerebral Hemorrhage Rats
Baihui-penetrating-Qubin acupuncture could reduce oxidative stress and neuronal apoptosis, at least in part, through the SIRT1/FOXO1 signaling pathway, improving neurological deficits and neuropathological damage after ICH. These findings suggest that Baihui-penetrating-Qubin acupuncture is an effective therapy for ICH, as well as targeting SIRT1 signaling to promote neuron survival could be a potential therapeutic strategy.
Authors
- Yuet Wai Kan (ORCID: https://orcid.org/0000-0003-0117-0100)
- Wenzhen Duan (ORCID: https://orcid.org/0000-0001-5933-6308)
- Hongtao Cao (ORCID: https://orcid.org/0000-0002-4458-4621)
- Xueping Yu
- Mingyue Li (ORCID: https://orcid.org/0000-0001-7215-4103)
- Lei Zheng
- Wei Zou (ORCID: https://orcid.org/0000-0003-2504-9970)
- Shanshan Dong (ORCID: https://orcid.org/0000-0003-3482-094X)
- Enli Luo
- Xiaohong Dai
Institutions
- Guizhou University (CN)
- Shenzhen University (CN)
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/brb3.70095
- Citations
- 7
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 2.58
Funders
- National Natural Science Foundation of China
- Shenzhen Municipal Science and Technology Innovation Council