Hsa_circRNA_100791 Modulates Trim13 Through Sponging miR-487b-5p to Facilitate Inflammation in Allergic Rhinitis
Our study demonstrated that hsa_circRNA_100791 mitigates the inhibitory effect of miR-487b-5p on Trim13 by directly binding to miR-487b-5p. This interaction regulates the expression of inflammatory factors and facilitates AR. Thus, hsa_circRNA_100791 could be a promising new therapeutic target for AR.
Authors
- Yisha Wu (ORCID: https://orcid.org/0000-0002-9751-2461)
- De Yun Wang (ORCID: https://orcid.org/0000-0002-0909-2963)
- Kaiyue Sun
- Xiaoxue Zi
- Yuzhu Wan (ORCID: https://orcid.org/0000-0001-6184-5902)
- Li Shi (ORCID: https://orcid.org/0000-0002-4162-7876)
- Jian Wu (ORCID: https://orcid.org/0000-0002-3394-1507)
- Peng Jin (ORCID: https://orcid.org/0000-0002-5696-2095)
Institutions
- Shandong University (CN)
- National University of Singapore (SG)
- Second Hospital of Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Binzhou People's Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/jir.s485165
- Citations
- 1
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.23