The new age of the phage

The discovery of viruses that can devour bacteria, bacteriophages (phages), was in 1915. Phages are ubiquitous, outnumbering the organisms they devour, and genomically, morphologically, and ecologically diverse. They were critical in our development of molecular biology and biotechnology tools and have been used as therapeutics for over 100 years, primarily in Eastern Europe with thousands of patients from all over the world treated in Georgia. The rise of antimicrobial resistance and the lack of new antimicrobials, has brought them back into the spotlight dawning the New Age of the Phage. This special issue will provide further insight to phage diversity across ecosystems, including humans, animals, and plants, i.e. the basis of a One Health approach, and the requirements for turning phages into viable medicines for the many and not just for the few.

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Publication Details

Journal
Essays in Biochemistry
Published
2024-12-01
DOI
https://doi.org/10.1042/ebc20240037
Citations
5
Primary Topic
Bacteriophages and microbial interactions
Type
article
Field-Weighted Citation Impact
2.29

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article

The new age of the phage

Joanne M. Santini
5 citations
Essays in Biochemistry
Bacteriophages and microbial interactions
2.29
article

The new age of the phage

Joanne M. Santini
article en
5 citations

Abstract

The discovery of viruses that can devour bacteria, bacteriophages (phages), was in 1915. Phages are ubiquitous, outnumbering the organisms they devour, and genomically, morphologically, and ecologically diverse. They were critical in our development of molecular biology and biotechnology tools and have been used as therapeutics for over 100 years, primarily in Eastern Europe with thousands of patients from all over the world treated in Georgia. The rise of antimicrobial resistance and the lack of new antimicrobials, has brought them back into the spotlight dawning the New Age of the Phage. This special issue will provide further insight to phage diversity across ecosystems, including humans, animals, and plants, i.e. the basis of a One Health approach, and the requirements for turning phages into viable medicines for the many and not just for the few.

Essays in BiochemistryVol. 68(5)
Institute of Structural and Molecular Biology (GB), University College London (GB)
Biotechnology and Biological Sciences Research Council
Life in Land
Openalex Percentile: Top 12%
Bacteriophages and microbial interactions
2.29
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The new age of the phage — Joanne M. Santini · Essays in Biochemistry (2024) | TGRS Research Map | TGRS