Prescribing Patterns and Off-Label Use of Gabapentinoid Agents at Dhulikhel Hospital, Nepal: A Cross-Sectional Study

This study highlights the extensive off-label and sub-therapeutic use of gabapentinoids at Dhulikhel Hospital and reveals significant gaps in patient knowledge. This emphasizes the need for stricter prescribing guidelines, improved healthcare provider education, and better patient information to optimize the use and minimize risks. The frequent prescription of low-dose pregabalin for neuropathic pain raises the possibility that it may be used for night-time sedation rather than for pain management, indicating the need for further investigation.

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Publication Details

Journal
Journal of Pain Research
Published
2024-12-01
DOI
https://doi.org/10.2147/jpr.s493542
Citations
2
Primary Topic
Pharmaceutical studies and practices
Type
article
Field-Weighted Citation Impact
2.22
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article

Prescribing Patterns and Off-Label Use of Gabapentinoid Agents at Dhulikhel Hospital, Nepal: A Cross-Sectional Study

Rajan Kumar Shrestha, David Woods, Durga Bista, Santusta Adhikari
2 citations
Journal of Pain Research
Pharmaceutical studies and practices
2.22
article

Prescribing Patterns and Off-Label Use of Gabapentinoid Agents at Dhulikhel Hospital, Nepal: A Cross-Sectional Study

Rajan Kumar Shrestha, David Woods, Durga Bista, Santusta Adhikari
article en
2 citations

Abstract

This study highlights the extensive off-label and sub-therapeutic use of gabapentinoids at Dhulikhel Hospital and reveals significant gaps in patient knowledge. This emphasizes the need for stricter prescribing guidelines, improved healthcare provider education, and better patient information to optimize the use and minimize risks. The frequent prescription of low-dose pregabalin for neuropathic pain raises the possibility that it may be used for night-time sedation rather than for pain management, indicating the need for further investigation.

Journal of Pain ResearchVol. Volume 17
Vilnius University (LT), Dhulikhel Hospital (NP), Kathmandu University (NP)
Openalex Percentile: Top 10%
Pharmaceutical studies and practices
2.22
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Prescribing Patterns and Off-Label Use of Gabapentinoid Agents at Dhulikhel Hospital, Nepal: A Cross-Sectional Study — Rajan Kumar Shrestha, David Woods, et al. · Journal of Pain Research (2024) | TGRS Research Map | TGRS