Synthesis and Study of Luminescent, Anti-Mao, and Antioxidant Properties of (2E)-3-Aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones and Their Pyrazoline Derivatives
By condensation of 1-(4-alkoxyphenyl)ethanones with aromatic aldehydes in the presence of sodium hydroxide in an aqueous-ethanol solution, (2E)-3-aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones were obtained. Cyclization of these latter with phenylhydrazine in an acidic medium leads to the corresponding 5-aryl-3-(4-alkoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazoles. The luminescent, antimonoamine oxidase, and antioxidant properties of the compounds obtained were studied.
Authors
- H. А. Panosyan (ORCID: https://orcid.org/0000-0001-8311-6276)
- Anahit E. Pogosyan (ORCID: https://orcid.org/0000-0001-8776-1483)
- S. G. Israelyan (ORCID: https://orcid.org/0009-0000-8088-1060)
- R. P. Mkhitaryan (ORCID: https://orcid.org/0009-0009-6277-2747)
- G. S. Grigoryan (ORCID: https://orcid.org/0000-0002-0675-735X)
- Hasmik R. Sargsyan (ORCID: https://orcid.org/0000-0002-0215-6012)
- R. E. Muradyan (ORCID: https://orcid.org/0000-0002-4110-9454)
- Gohar Arajyan (ORCID: https://orcid.org/0009-0002-7638-4162)
- A. U. Isakhanyan (ORCID: https://orcid.org/0000-0002-1713-4908)
- H. V. Gasparyan (ORCID: https://orcid.org/0000-0002-8555-3733)
- N. Z. Hakobyan (ORCID: https://orcid.org/0000-0002-3095-5938)
- А. А. Harutyunyan (ORCID: https://orcid.org/0000-0003-0641-5453)
- Nvard Pahutyan (ORCID: https://orcid.org/0000-0002-3864-8705)
- A. S. Grigoryan
Institutions
- Yerevan State University (AM)
- Institute of Fine Organic Chemistry of Scientific - Technological Center of Organic and Pharmaceutical Chemistry (AM)
Publication Details
- Journal
- Russian Journal of General Chemistry
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1134/s1070363224110057
- Citations
- 1
- Primary Topic
- Synthesis of Organic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.45