Comparison of Basal Core Promoter Region Mutation and Precore Mutation among Monoinfected Hepatitis B Virus and Coinfected Hepatitis B Virus with Human Immunodeficiency Virus Patients

The BCP mutants in our study had a high percentage of HBeAg negativity, low DNA levels, and mildly elevated ALT levels, mimicking inactive carriers. BCP mutants have a strong association with chronic liver diseases, so identifying chronic inactive HBV patients harboring the BCP mutant is necessary, and they require a close follow-up regimen.