The effect of Arsenic trioxide and its combination with Oxaliplatin and Docetaxel on the induction of autophagy and expression of LC3 and Beclin-1 genes in AGS and MKN-45 Gastric cancer cell lines
The combination of two therapeutic agents represents a promising strategy for inducing autophagy and gene expression related to apoptosis in gastric cancer cells. This approach exerted a more substantial influence on cell apoptosis and necrosis than single-drug treatments, underscoring its potential as an effective therapeutic option.
Authors
- Ahmad Majd (ORCID: https://orcid.org/0000-0003-3707-7581)
- Mohsen Nikbakht (ORCID: https://orcid.org/0000-0001-6621-5424)
- Seyed Asadoullah Mousavi (ORCID: https://orcid.org/0009-0003-2658-4825)
- Shadi Babaei (ORCID: https://orcid.org/0000-0001-5248-4818)
Institutions
- Iran University of Medical Sciences (IR)
- Islamic Azad University North Tehran Branch (IR)
- Stem Cell Technology Research Center (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Advanced Pharmaceutical Bulletin
- Published
- 2024-12-04
- DOI
- https://doi.org/10.34172/apb.42747
- Citations
- 1
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Tehran University of Medical Sciences and Health Services