Efficacy and Security of Improved Thumbtack-Type Cervical Cold Knife Conization to Treat Cervical High-Grade Epithelial Lesions

Background and Objective: Women’s second-most prevalent malignancy is cervical cancer. After cervical cancer screening became widespread, cervical intraepithelial neoplasia (CIN) increased but cervical carcinoma decreased. This study aimed to evaluate the safety and efficacy of the new thumbtack-type cervical cold knife cone in cervical high-level epithelial neoplasia. Materials and Methods: A retrospective analysis was conducted of the clinical data of 114 patients with cervical high-grade epithelial fibrosis at The Affiliated Hospital of Guizhou Medical University Hospital from January, 2019 to December, 2019. The study group consisted of 55 patients with underlying thumbtack-type cervical cold knife taper (TCKC) and 59 patients with traditional cervical cold knife cutting (CKC) in the control group. The results of the two groups were analyzed, comparing surgical time, in-surgery bleeding and pathological results. Results: Compared with the control group, the difference in surgical time and bleeding, cone length and cone diameter was statistically significant (p<0.05) and the age comparison difference was not statistically significant. The difference between the study and control groups was not statistically significant in comparing the positive margin rate at the bottom of the cone (p>0.05). Conclusion: The surgical thoroughness and safety of thumbtack-type cervical cold knife conization were consistent with traditional cervical cold knife conization, but thumbtack-type cervical cold knife conization had the advantage of less bleeding tissue damage and a shorter surgery time, therefore being more minimally invasive than CKC. Compared with the traditional operation, the improved push-pin-type cervical conical surgery had the best outcomes.