Socio-demographic disparities in colorectal cancer in Brazil, 1990-2019

ABSTRACT In the world, colorectal cancer presents high rates of incidence and mortality, with differences according to the level of sociodemographic development. The objective of this study was to analyze the sociodemographic disparities of colorectal cancer in the Brazilian population aged 30 and older. This is a time series study of incidence, mortality, disability-adjusted life years (DALY), and prevalence, by sex, in Brazil and its Federal Units (FU) states from 1990 to 2019. The trend was estimated using Joinpoint regression analysis, and the Socio-Demographic Index (SDI) was used in the correlation analysis. The data analyzed were estimated by the Global Burden of Diseases Study 19. In Brazil and its states, the highest rates of these indicators were observed in males, with an increasing trend in both sexes. There was a positive association between SDI and all the analyzed indicators except for DALY in men. The differences in rates and trends between the states reflect the country’s development processes, such as urbanization and industrialization. More developed states have high rates with stable trends, while less developed states exhibit the opposite behavior, suggesting improved access to healthcare services and diagnosis.