Neural activity during working memory predicts clinical response to computerized executive function training prior to cognitive processing therapy
Greater activity of frontal regions implicated in working memory may serve as a biomarker of response to a novel treatment in veterans with PTSD. Individuals with greater regional responsiveness benefited more from treatment that targeted cognitive dysfunction than treatment that did not include active cognitive training. Clinically, findings could inform our understanding of treatment mechanisms and may contribute to better personalization of treatment.
Authors
- Amy J. Jak (ORCID: https://orcid.org/0000-0001-8588-1430)
- Jessica Bomyea (ORCID: https://orcid.org/0000-0001-9853-135X)
- Delaney K. Davey (ORCID: https://orcid.org/0000-0003-4784-8925)
- Laura D. Crocker (ORCID: https://orcid.org/0000-0001-8713-1211)
- Morgan M. Caudle (ORCID: https://orcid.org/0000-0003-3556-2313)
Institutions
- San Diego State University (US)
- University of California San Diego (US)
- University of Illinois Chicago (US)
- VA San Diego Healthcare System (US)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1017/s0033291724003106
- Citations
- 1
- Primary Topic
- Posttraumatic Stress Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.64