The Immunosuppressive Functions of Eosinophils Are Compromised in Patients With Allergic Rhinitis, Particularly Concerning Rab27a Expression
Eosinophils have immune regulatory functions, which are controlled by the expression of Rab27a. Regulation of Rab27a can improve the immune regulatory functions of eosinophils. The data suggest that inhibition of Rab27a can be a drug candidate for the treatment of eosinophil-related disorders.
Authors
- Xuejie Xu (ORCID: https://orcid.org/0000-0003-3376-3410)
- Minyao Li (ORCID: https://orcid.org/0000-0002-0458-546X)
- Xiaojun Xiao (ORCID: https://orcid.org/0000-0002-1195-0541)
- Yun Liao
- Ping–Chang Yang (ORCID: https://orcid.org/0000-0002-6806-9464)
- Yu Liu (ORCID: https://orcid.org/0000-0001-7015-9357)
- Gui Yang (ORCID: https://orcid.org/0000-0002-5413-0121)
- Shuo Song (ORCID: https://orcid.org/0009-0009-6232-635X)
Institutions
- Shenzhen University (CN)
- Longgang Central Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/iid3.70091
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation