#ECR-Poster-06 Transcriptome analysis of patient derived microphthalmia and myopia optic vesicles identifies key molecular pathways influencing axial length

Conclusions I-wave amplitude associated significantly with the myopia risk locus, supporting the importance of cone-driven signals in myopia development and adding evidence that this risk locus specifically affects OFF pathway signals.

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Published
2024-10-01
DOI
https://doi.org/10.1136/bmjoo-2024-ukegg.8
Primary Topic
Ocular Disorders and Treatments
Type
article
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article

#ECR-Poster-06 Transcriptome analysis of patient derived microphthalmia and myopia optic vesicles identifies key molecular pathways influencing axial length

Philippa Harding, Nicholas Owen, Daniel Jackson, Mariya Moosajee et al.
Ocular Disorders and Treatments
article

#ECR-Poster-06 Transcriptome analysis of patient derived microphthalmia and myopia optic vesicles identifies key molecular pathways influencing axial length

Philippa Harding, Nicholas Owen, Daniel Jackson, Mariya Moosajee, Jonathan Eintracht
article en

Abstract

Conclusions I-wave amplitude associated significantly with the myopia risk locus, supporting the importance of cone-driven signals in myopia development and adding evidence that this risk locus specifically affects OFF pathway signals.

University College London (GB)
Zero hunger
Openalex Percentile: Top 74%
Ocular Disorders and Treatments
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