Investigating a Nonlinear Fractional Evolution Control Model Using W-Piecewise Hybrid Derivatives: An Application of a Breast Cancer Model

Many real-world phenomena exhibit multi-step behavior, demanding mathematical models capable of capturing complex interactions between distinct processes. While fractional-order models have been successfully applied to various systems, their inherent smoothness often limits their ability to accurately represent systems with discontinuous changes or abrupt transitions. This paper introduces a novel framework for analyzing nonlinear fractional evolution control systems using piecewise hybrid derivatives with respect to a nondecreasing function W(ι). Building upon the theoretical foundations of piecewise hybrid derivatives, we establish sufficient conditions for the existence, uniqueness, and Hyers–Ulam stability of solutions, leveraging topological degree theory and functional analysis. Our results significantly improve upon existing theoretical understanding by providing less restrictive conditions for stability compared with standard fixed-point theorems. Furthermore, we demonstrate the applicability of our framework through a simulation of breast cancer disease dynamics, illustrating the impact of piecewise hybrid derivatives on the model’s behavior and highlighting advantages over traditional modeling approaches that fail to capture the multi-step nature of the disease. This research provides robust modeling and analysis tools for systems exhibiting multi-step behavior across diverse fields, including engineering, physics, and biology.