On-demand treatment of hereditary angioedema attacks
The disparity between survey respondents' perception of treating early and actual time to OD administration is striking. Treatment-related anxiety was a common reason for delaying OD. Increased treatment intervals translated into progression of HAE attack severity, duration, and spread to other sites. Suboptimal management of attacks intensifies the HAE disease burden, underscoring the need for improved treatment options, guidance, and removal of OD administration barriers.
Authors
- Tomas Andriotti
- Cristine Radojicic
- Julie Ulloa
- Sandra C. Christiansen (ORCID: https://orcid.org/0009-0006-1576-4523)
- Sherry Danese
- Paula J. Busse (ORCID: https://orcid.org/0000-0002-0793-2906)
- H. James Wedner (ORCID: https://orcid.org/0000-0001-8428-6568)
- Paul Audhya
- Timothy Craig
- Vibha Desai
- Maeve O’Connor
- Christopher Utter
Institutions
- Duke University (US)
- Washington University in St. Louis (US)
- Mount Sinai Hospital (US)
- KalVista Pharmaceuticals (United States) (US)
Publication Details
- Journal
- Annals of Allergy Asthma & Immunology
- Published
- 2024-12-16
- DOI
- https://doi.org/10.1016/j.anai.2024.12.012
- Citations
- 12
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 5.26