Аnalysis of limonene and eugenol integration into the fixative as a characteristic of a sustained-release complex

This study explores the effectiveness of β-cyclodextrin (β-CD) as a carrier for essential oils (EOs), specifically d-limonene, and eugenol, within biodegradable delivery systems. Inclusion complexes were prepared via coprecipitation and analyzed using Fourier-transform infrared spectroscopy. FTIR analysis confirmed the encapsulation, indicated by the shift in the O-H stretching vibrations of β-CD and a reduction in the intensity of the C-H stretching vibrations of d-limonene, which suggests successful molecular inclusion. Quantitative assessments revealed that β-CD complexes achieved a d-limonene payload of approximately 2–5 %, with an observed increase in peak areas of C-H bonds between 850–900 cm–1 by up to 6–10 %. For eugenol, the efficiency of integration into β-CD was 37.5 %.