Clinical relevance of calprotectin in patients with perianal fistulas in Crohn's disease and cryptoglandular fistulas
Crohn's disease and cryptoglandular perianal fistulas differ in FC levels. Local fistula calprotectin production did not explain this difference, implying FC reflects the luminal condition. A correlation exists between scraping calprotectin levels and Crohn's disease fistula severity, which could be clinically relevant for prognostic cohorts and tailored treatment.
Authors
- Marte Becker (ORCID: https://orcid.org/0000-0002-7881-4958)
- Toer Stevens (ORCID: https://orcid.org/0000-0002-2988-7966)
- Manon E. Wildenberg (ORCID: https://orcid.org/0000-0003-0671-818X)
- Geert D’Haens (ORCID: https://orcid.org/0000-0003-2784-4046)
- F de Voogd (ORCID: https://orcid.org/0000-0003-4058-252X)
- K Gecse (ORCID: https://orcid.org/0000-0003-4830-142X)
- Christianne J. Buskens
Institutions
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- United European Gastroenterology Journal
- Published
- 2024-12-16
- DOI
- https://doi.org/10.1002/ueg2.12622
- Citations
- 9
- Primary Topic
- Anorectal Disease Treatments and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 5.15