External Validation of Brief Resolved Unexplained Events Prediction Rules for Serious Underlying Diagnosis
Results of this multicenter cohort study show that the BRUE prediction rules outperformed the AAP higher-risk criteria on external geographical validation, and performance improved after recalibration. These rules provide clinicians and families with a more precise tool to support decision-making, grounded in individual risk tolerance.
Authors
- Jessica L. Foulds (ORCID: https://orcid.org/0000-0002-2471-0432)
- Joanna Holland (ORCID: https://orcid.org/0000-0002-4003-4227)
- Falla Jin
- Émy Philibert
- Ye Shen (ORCID: https://orcid.org/0000-0002-6662-0048)
- Ran D. Goldman (ORCID: https://orcid.org/0000-0001-8318-5415)
- Kara Picco
- Nardin Kirolos (ORCID: https://orcid.org/0009-0003-2658-1624)
- Émilie Harnois
- Matthew Donlan
- Josée Anne Gagnon
- Shawn Lee (ORCID: https://orcid.org/0000-0001-6897-634X)
- Chris Novak (ORCID: https://orcid.org/0000-0002-1463-2557)
- Peter J. Gill (ORCID: https://orcid.org/0000-0002-6253-1312)
- Susan Akbaroghli (ORCID: https://orcid.org/0000-0001-5510-4673)
- Joel S. Tieder (ORCID: https://orcid.org/0000-0001-6539-7115)
- Sanjay Mahant (ORCID: https://orcid.org/0000-0003-0487-5835)
- Zerlyn Lee
- Jeffrey N. Bone (ORCID: https://orcid.org/0000-0001-7704-1677)
- Nassr Nama (ORCID: https://orcid.org/0000-0002-0199-3599)
- Brigitte Parisien
- Parnian Hosseini
- Elisa Frizon-Peresa
- Ioulia Opotchanova
- Prathiksha Nalan
- Praveen Rajasegaran
- Melody Wyslobicky
- Raman Chawla
- Anupam Sehgal
- Polina Kyrychenko
- Marie-Pier Goupil
- Juliette Dufrense
- Martin Ogwuru
Institutions
- Seattle Children's Hospital (US)
- University of British Columbia (CA)
- University of Alberta (CA)
- University of Calgary (CA)
- University of Toronto (CA)
- University of Washington (US)
- Queen's University (CA)
- Montreal Children's Hospital (CA)
- Izaak Walton Killam Health Centre (CA)
- Kingston General Hospital (CA)
- Hospital for Sick Children (CA)
- Alberta Children's Hospital (CA)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- SickKids Foundation (CA)
- BC Children's Hospital (CA)
- Research Network (United States) (US)
- Stollery Children's Hospital (CA)
- Université Laval (CA)
- McGill University (CA)
- Université de Montréal (CA)
Publication Details
- Journal
- JAMA Pediatrics
- Published
- 2024-12-16
- DOI
- https://doi.org/10.1001/jamapediatrics.2024.4399
- Citations
- 6
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 2.51