Human Papilloma Virus Circulating Cell-Free DNA Kinetics in Patients with Cervical Cancer Undergoing Definitive Chemoradiation
HPV cfDNA levels change dynamically during chemoRT. HPV cfDNA levels at follow-up predict RFS, and delivery of therapeutic HPV vaccine with chemoRT was linked to rapid HPV cfDNA decline. Monitoring HPV cfDNA during and after chemoRT may guide tailoring of personalized treatment.
Authors
- Peng Wei (ORCID: https://orcid.org/0000-0001-7758-6116)
- Tatiana Cisneros Napravnik
- Weihong Xiao (ORCID: https://orcid.org/0000-0003-4132-213X)
- Ann H. Klopp (ORCID: https://orcid.org/0000-0002-2081-0735)
- David Fuentes (ORCID: https://orcid.org/0000-0002-2572-6962)
- Adam Grippin (ORCID: https://orcid.org/0000-0002-8076-4240)
- Lilie L. Lin (ORCID: https://orcid.org/0000-0001-7681-8966)
- Megan C. Jacobsen (ORCID: https://orcid.org/0000-0002-1757-3628)
- Anuja Jhingran (ORCID: https://orcid.org/0000-0002-0697-1815)
- Aradhana M. Venkatesan (ORCID: https://orcid.org/0000-0002-5033-0820)
- Erica Lynn (ORCID: https://orcid.org/0000-0003-1954-0050)
- Lauren E. Colbert (ORCID: https://orcid.org/0000-0001-5806-4339)
- David Swanson (ORCID: https://orcid.org/0000-0003-3174-1656)
- Julie Sammouri (ORCID: https://orcid.org/0000-0002-3232-4865)
- Maura L. Gillison (ORCID: https://orcid.org/0000-0002-8145-5749)
- Olsi Gjyshi
- Aaron Seo (ORCID: https://orcid.org/0000-0002-8146-4346)
- Kyoko Yoshida-Court (ORCID: https://orcid.org/0000-0002-7558-9943)
- Melissa Joyner (ORCID: https://orcid.org/0000-0003-1370-5061)
Institutions
- The University of Texas MD Anderson Cancer Center (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-12-16
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-2343
- Citations
- 7
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 2.71