<scp>TSPO</scp>‐<scp>PET</scp> in pre‐surgical evaluations: Correlation of neuroinflammation and <scp>SEEG</scp> epileptogenicity mapping in drug‐resistant focal epilepsy

These findings suggest that neuroinflammation may be a molecular substrate of the EZ in non-lesional focal epilepsy. Identifying the EZ inpatients with complex DRFE and inconclusive MRI/[<sup>18</sup>F]FDG-PET imaging is essential to improve resective surgery outcomes. Combining TSPO-PET imaging with SEEG recordings may help bridge this gap.

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Publication Details

Journal
Epilepsia
Published
2024-12-16
DOI
https://doi.org/10.1111/epi.18182
Citations
9
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
3.47
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article

TSPO‐PET in pre‐surgical evaluations: Correlation of neuroinflammation and SEEG epileptogenicity mapping in drug‐resistant focal epilepsy

Nozar Aghakhani, Jennifer Kilmer, Michel Bottlaender, Claire Leroy et al.
9 citations
Epilepsia
Epilepsy research and treatment
3.47
article

TSPO‐PET in pre‐surgical evaluations: Correlation of neuroinflammation and SEEG epileptogenicity mapping in drug‐resistant focal epilepsy

Nozar Aghakhani, Jennifer Kilmer, Michel Bottlaender, Claire Leroy, Anne Herbrecht, Nicolas Tournier, Ana‐maria Petrescu, Delphine Taussig, Sébastian Rodrigo, Viviane Bouilleret
article en
9 citations

Abstract

These findings suggest that neuroinflammation may be a molecular substrate of the EZ in non-lesional focal epilepsy. Identifying the EZ inpatients with complex DRFE and inconclusive MRI/[<sup>18</sup>F]FDG-PET imaging is essential to improve resective surgery outcomes. Combining TSPO-PET imaging with SEEG recordings may help bridge this gap.

EpilepsiaVol. 66(2)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Université Paris-Saclay (FR), Institut d'Imagerie Biomédicale (FR), Laboratoire d’Imagerie Biomédicale (FR), CEA Paris-Saclay (FR)
Good health and well-being
Openalex Percentile: Top 6%
Epilepsy research and treatment
3.47
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<scp>TSPO</scp>‐<scp>PET</scp> in pre‐surgical evaluations: Correlation of neuroinflammation and <scp>SEEG</scp> epileptogenicity mapping in drug‐resistant focal epilepsy — Nozar Aghakhani, Jennifer Kilmer, et al. · Epilepsia (2024) | TGRS Research Map | TGRS