Longitudinal cytokine profile in severe <scp>COVID</scp>‐19 and multisystem inflammatory syndrome in children: A single centre study from <scp>Egypt</scp>

Our study underpinned patterns of cytokine response in severe COVID-19 and MIS-C. There is a significant upregulation in pro-inflammatory cytokines (mainly G-CSF, IL-10, HMGB1, TNF-α, IL-6, IL-8 and INF-gamma). These biomarkers that could imply on the severity rating and treatment strategies, should be preferentially assessed in SARS-CoV-2 associated immunological events.

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Publication Details

Journal
Journal of Paediatrics and Child Health
Published
2024-12-16
DOI
https://doi.org/10.1111/jpc.16746
Primary Topic
Kawasaki Disease and Coronary Complications
Type
article
Field-Weighted Citation Impact
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article

Longitudinal cytokine profile in severe COVID‐19 and multisystem inflammatory syndrome in children: A single centre study from Egypt

Amer Alshengeti, Doaa Mosad Mosa, Dina S. El‐Agamy, Mai S Korkor et al.
Journal of Paediatrics and Child Health
Kawasaki Disease and Coronary Complications
article

Longitudinal cytokine profile in severe COVID‐19 and multisystem inflammatory syndrome in children: A single centre study from Egypt

Amer Alshengeti, Doaa Mosad Mosa, Dina S. El‐Agamy, Mai S Korkor, Ali Sobh, Marwa H. Elnagdy, Waad A. Samman, Abdulhadi Almazroea, Hany M. Abo‐Haded, Abdulsalam Alawfi, Rawan Bafail
article en

Abstract

Our study underpinned patterns of cytokine response in severe COVID-19 and MIS-C. There is a significant upregulation in pro-inflammatory cytokines (mainly G-CSF, IL-10, HMGB1, TNF-α, IL-6, IL-8 and INF-gamma). These biomarkers that could imply on the severity rating and treatment strategies, should be preferentially assessed in SARS-CoV-2 associated immunological events.

Journal of Paediatrics and Child HealthVol. 61(2)
Mansoura University (EG), Taibah University (SA), Children's Hospital Mansoura University (EG)
Good health and well-being
Openalex Percentile: Top 57%
Kawasaki Disease and Coronary Complications
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