New Arylalkenyl α‐Pyrones from <i>Cryptocarya densiflora</i>
Four previously undescribed arylalkenyl α-pyrones, designated as crydensiones A‒D (1‒4), were isolated from the twigs and leaves of Cryptocarya densiflora. Their structures were determined through comprehensive spectroscopic analyses together with quantum chemical calculations of electronic circular dichroism and nuclear magnetic resonance data. All isolates were assessed for cytotoxicity against HCT-116 (colon), A549 (lung), and MDA-MB-231 (breast) cancer cell lines; however, none demonstrated significant activity.
Authors
- Jun‐Juan Xue
- Chuan‐Rui Zhang (ORCID: https://orcid.org/0000-0002-0376-0369)
- Li Rao (ORCID: https://orcid.org/0009-0005-7833-4208)
- Jie Meng (ORCID: https://orcid.org/0000-0002-4485-4812)
- Lei Miao (ORCID: https://orcid.org/0000-0001-7670-4782)
- Yu Zhang (ORCID: https://orcid.org/0009-0009-6733-6338)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Kunming Institute of Botany (CN)
- Chongqing University (CN)
- Chinese Academy of Sciences (CN)
- Shanghai Institute of Materia Medica (CN)
- Advanced Research Institute (US)
- Drug Discovery Laboratory (Norway) (NO)
- Chongqing Medical and Pharmaceutical College (CN)
Publication Details
- Journal
- Chemistry & Biodiversity
- Published
- 2024-12-16
- DOI
- https://doi.org/10.1002/cbdv.202403120
- Citations
- 3
- Primary Topic
- Traditional and Medicinal Uses of Annonaceae
- Type
- article
- Field-Weighted Citation Impact
- 0.88