Single-Cell Sequencing Combined with Transcriptome Sequencing to Explore the Molecular Mechanisms Related to Skin Photoaging
This research revealed the underlying molecular mechanisms of photoaging, indicating that key genes such as Atp2b1 and Tspan13 play crucial roles in the regulation of immune cell infiltration and metabolic pathways. These findings provide a new theory for the treatment of photoaging and provide prospective targets for the advancement of relevant drugs.
Authors
- Jia He (ORCID: https://orcid.org/0000-0002-7717-8574)
- Hao Yang (ORCID: https://orcid.org/0000-0003-2214-9474)
- Meng Chen (ORCID: https://orcid.org/0009-0005-3537-9027)
- Xinru Hu (ORCID: https://orcid.org/0009-0000-4740-2646)
- Bowen Tan (ORCID: https://orcid.org/0000-0002-5734-1602)
- Lei Zhang (ORCID: https://orcid.org/0009-0000-9738-4685)
- Liang Cao (ORCID: https://orcid.org/0000-0003-0068-4273)
- Xi Duan
- Shuang Du (ORCID: https://orcid.org/0009-0000-3976-708X)
Institutions
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/jir.s496328
- Citations
- 3
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.60
Funders
- National Natural Science Foundation of China
- Natural Science Foundation for Young Scientists of Shanxi Province
- Young Scientists Fund