Triboelectric multilayered electrospun co-polyamide-based wound dressings with inherent antibacterial properties

Abstract Wound healing is a challenging problem to healthcare and society, requiring the development of advanced materials that can enhance tissue rejuvenation and prevent infection. This article presents the design and synthesis of a multilayered copolyamide based electrospun membrane for wound healing applications. The dressing is engineered using a combination of copolymerisation and electrospinning techniques. The unique porous architecture, hydrophilicity, and adequate mechanical and thermal stability make the developed materials ideal candidates for skin regeneration. The inherent antibacterial effectiveness of the membrane was investigated on a range of pathogens that cause wound infections. The cytocompatibility of the membrane was studied on human monocyte cell lines, which play a vital role in immune response and skin regeneration. This multilayered membrane embodies a promising strategy for promoting wound care consequences through its combination of biocompatibility, structural integrity, and inherent antibacterial properties. The potential impact of this research on the field of wound healing is significant and inspiring. Graphical abstract