Pancreatic Sarcoidosis: A Rare Manifestation of Systemic Sarcoidosis

Sarcoidosis is a chronic granulomatous disease with multisystemic involvement with unspecified aetiology. Pancreatic involvement is a rare manifestation of systemic sarcoidosis and is often detected in postmortem studies. This clearly implies the rarity of the disease and its diagnostic challenges. Despite having various biochemical markers and imaging techniques, the only definitive method of diagnosis is the histological examination of the lesion. We present a patient with abdominal pain associated with obstructive jaundice, where imaging demonstrated features of pulmonary sarcoidosis along with a pancreatic head mass. Endoscopic ultrasound-guided biopsy demonstrated pancreatic non-caseating granulomas suggestive of sarcoidosis. Subsequently, the patient underwent biliary stenting and was started on glucocorticoid therapy.