Delayed and recurrent surgical site infection from resorbed bone fragment after autologous cranioplasty: a case report

Decompressive craniectomy is one of the most common procedures for managing severe traumatic brain injury. Cranioplasty plays a vital role in restoring the integrity of the skull and preventing complications that may arise after a decompressive craniectomy. This case report presents a 24-year-old woman who underwent cranioplasty with a cryopreserved autologous bone flap. Initially successful, the procedure was later complicated by a delayed surgical site infection and methicillin-resistant Staphylococcus aureus osteomyelitis, ultimately resulting in complete resorption of the bone flap. The report discusses the consequences of autologous bone flap resorption and surgical site infection, highlighting the critical need for effective sterilization and proper bone storage techniques. This case emphasizes the necessity of exploring alternative strategies to improve cranioplasty outcomes and minimize the risk of infection.