Ferric nitrene-promoted anti-Markovnikov ring-opening of epoxides and nucleophilic functionalization of benzylic C–H bonds under photo-irradiation
This paper describes a ferric nitrene/photoredox dual-catalyzed anti-Markovnikov ring-opening of epoxides under neutral conditions for providing α-substituted acetophenones. A DFT-based calculation supported the reaction regioselectivity. The catalytic system could also be applied to the formation of C-O and C-N bonds <i>via</i> nucleophilic functionalization of benzylic C-H bonds.
Authors
- Guanyinsheng Qiu (ORCID: https://orcid.org/0000-0002-6587-8522)
- Rui Qi
- Ming Hou
- Minghao Jia (ORCID: https://orcid.org/0000-0002-5950-4284)
- Linli He (ORCID: https://orcid.org/0000-0001-9297-4379)
- Tianwen Bai (ORCID: https://orcid.org/0000-0003-1033-9756)
- Baoming Chen (ORCID: https://orcid.org/0000-0003-1891-8752)
- Zhide Zhang (ORCID: https://orcid.org/0000-0003-0599-6567)
Institutions
- Wenzhou University (CN)
- Jiaxing University (CN)
- Jiaxing Vocational Technical College (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-12-16
- DOI
- https://doi.org/10.1039/d4cc04236k
- Citations
- 1
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.25