Assessment Of Essential Trace Elements, Acute Phase Reactants, And Biochemical Parameters In Stone Mine Workers And Healthy Controls In Western Rajasthan

Introduction:Silicosis is a serious lung disease caused by long-term exposure to crystalline silica dust in the workplace.The risk and development of silicosis are significantly influenced by the mineral composition of work environments.Aim: The aim of this study is to evaluate the connection between mineral content in industrial environments and the likelihood of developing silicosis.Methodology: This is a comparative cross-sectional study designed to assess the levels of essential trace elements, acute phase reactants, and biochemical parameters in stone mine workers and healthy controls in the western Rajasthan region.Result: Pearson correlation indicated a significant relationship between increased occupational exposure and higher levels of copper, CRP, and ferritin, while lower zinc and vitamin D levels were also correlated with increased exposure.In conclusion, The study revealed significant differences in essential trace elements, acute phase reactants, and vitamin levels between stone mine workers and healthy controls.The findings underscore the need for targeted health interventions to address nutritional deficiencies and monitor inflammatory markers among mine workers to mitigate health risks associated with occupational exposure.