Decreased telomerase activity and shortened telomere length in infants whose mothers have gestational diabetes mellitus and increased severity of telomere shortening in male infants
The poor intrauterine environment in pregnant women with GDM increases telomere attrition and reduces TE activity, which may be potential genetic risk factors for an increased risk of metabolic diseases in offspring later in life due to intrauterine reprogramming.
Authors
- Mingming Zheng (ORCID: https://orcid.org/0000-0003-0611-5581)
- Shuhua Liu (ORCID: https://orcid.org/0000-0002-5133-329X)
- Xianxia Chen
- Yan Cheng (ORCID: https://orcid.org/0000-0002-0919-672X)
- Liping Xu (ORCID: https://orcid.org/0000-0003-4434-1213)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-6286-6227)
- Dehong Liu (ORCID: https://orcid.org/0000-0003-1934-4009)
Institutions
- Anhui Medical University (CN)
- Anhui Provincial Children's Hospital (CN)
- Hefei Infectious Disease Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-12-16
- DOI
- https://doi.org/10.3389/fendo.2024.1490336
- Citations
- 3
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 3.33
Funders
- Anhui Provincial Department of Education