Brief Report: Associations Between Gender and Solicited Adverse Events After Passive Infusion of VRC01 or Placebo in HVTN 704/HPTN 085
This is the first report of associations between gender and solicited AEs after monoclonal antibody infusion. GM participants reported more events; severity was low. HIV prevention trials must engage and support GM individuals to best evaluate tolerability of novel agents.
Authors
- Daniel J Mangini
- Javier R. Lama (ORCID: https://orcid.org/0000-0002-4983-5725)
- Robert De La Grecca
- Michele P. Andrasik (ORCID: https://orcid.org/0000-0003-1952-7825)
- Yunda Huang (ORCID: https://orcid.org/0000-0003-1546-6172)
- Annet Davis (ORCID: https://orcid.org/0000-0002-5356-7321)
- Srilatha Edupuganti (ORCID: https://orcid.org/0000-0001-6566-9969)
- Myron S. Cohen (ORCID: https://orcid.org/0000-0001-5917-9664)
- Sheryl Zwerski
- Delivette Castor (ORCID: https://orcid.org/0000-0002-0988-9489)
- Alison C. Roxby (ORCID: https://orcid.org/0000-0001-9449-8062)
- Shelly Karuna (ORCID: https://orcid.org/0000-0001-5946-9733)
- Moni B. Neradilek (ORCID: https://orcid.org/0000-0002-3154-6597)
- Deborah Theodore (ORCID: https://orcid.org/0000-0001-8998-113X)
- Magdalena E. Sobieszczyk (ORCID: https://orcid.org/0000-0002-7112-3118)
- P. Andrew (ORCID: https://orcid.org/0000-0003-0357-0597)
- Gail Broder (ORCID: https://orcid.org/0000-0002-5352-3097)
- Mary Marovich (ORCID: https://orcid.org/0000-0002-8400-3748)
- Kevin Gillespie
- Yi H. Wu
- Juan Hinojosa
Institutions
- University of North Carolina at Chapel Hill (US)
- Family Health International 360 (US)
- National Institutes of Health (US)
- Emory University (US)
- University of Washington (US)
- Asociación Civil Impacta Salud y Educación (PE)
- Columbia University Irving Medical Center (US)
- Fred Hutch Cancer Center (US)
- Asociación para la Conservación de la Cuenca Amazónica (PE)
- National Institute of Allergy and Infectious Diseases (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2024-12-16
- DOI
- https://doi.org/10.1097/qai.0000000000003582
- Primary Topic
- Healthcare cost, quality, practices
- Type
- article
- Field-Weighted Citation Impact
- 0.00