Sudden vision loss in pregnancy: Wernicke’s encephalopathy in a patient with hyperemesis gravidarum

Wernicke's encephalopathy, the acute phase of Wernicke-Korsakoff syndrome, is characterised as a triad of altered mental status, ocular signs and ataxia. Our patient presented with hyperemesis gravidarum, which is a rare aetiology of Wernicke's encephalopathy. The patient did not have any oculomotor abnormalities, which are more common and classically described in Wernicke's triad. The sudden visual loss in both eyes can be attributed to acute optic neuropathy. Our case highlights a unique ophthalmic presentation with retinal haemorrhages and optic disc oedema as unusual manifestations of Wernicke's encephalopathy. The dramatic and complete reversal of visual symptoms within 48 hours after starting parenteral thiamine retrospectively supports the diagnosis.

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Publication Details

Journal
BMJ Case Reports
Published
2024-12-01
DOI
https://doi.org/10.1136/bcr-2024-261085
Citations
1
Primary Topic
Alcoholism and Thiamine Deficiency
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article
Field-Weighted Citation Impact
0.37
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article

Sudden vision loss in pregnancy: Wernicke’s encephalopathy in a patient with hyperemesis gravidarum

Sunil Kumar Srinivas, Teena Mariet Mendonca, Gladys Rodrigues, Surabhi Subramanian
1 citations
BMJ Case Reports
Alcoholism and Thiamine Deficiency
0.37
article

Sudden vision loss in pregnancy: Wernicke’s encephalopathy in a patient with hyperemesis gravidarum

Sunil Kumar Srinivas, Teena Mariet Mendonca, Gladys Rodrigues, Surabhi Subramanian
article en
1 citations

Abstract

Wernicke's encephalopathy, the acute phase of Wernicke-Korsakoff syndrome, is characterised as a triad of altered mental status, ocular signs and ataxia. Our patient presented with hyperemesis gravidarum, which is a rare aetiology of Wernicke's encephalopathy. The patient did not have any oculomotor abnormalities, which are more common and classically described in Wernicke's triad. The sudden visual loss in both eyes can be attributed to acute optic neuropathy. Our case highlights a unique ophthalmic presentation with retinal haemorrhages and optic disc oedema as unusual manifestations of Wernicke's encephalopathy. The dramatic and complete reversal of visual symptoms within 48 hours after starting parenteral thiamine retrospectively supports the diagnosis.

BMJ Case ReportsVol. 17(12)
Manipal Academy of Higher Education (IN), Kasturba Medical College, Mangalore (IN), Kasturba Medical College, Manipal (IN)
Good health and well-being
Openalex Percentile: Top 32%
Alcoholism and Thiamine Deficiency
0.37
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