Safety and Efficacy of Metformin for Idiopathic Intracranial Hypertension: A U.S.-Based Real-World Data Retrospective Multicenter Cohort Study
The study indicates metformin's potential as a disease-modifying treatment in IIH, with improvements across multiple outcomes independent of weight loss. This suggests complex mechanisms at play, supporting further research through prospective clinical trials to confirm metformin's role in IIH management and its mechanisms of action.
Authors
- David Altschul (ORCID: https://orcid.org/0000-0002-5130-1378)
- Ahmed Saad Al Zomia (ORCID: https://orcid.org/0000-0002-7850-7229)
- Muhammed Amir Essibayi (ORCID: https://orcid.org/0000-0001-8325-2382)
- Adam Andrew Dmytriw (ORCID: https://orcid.org/0000-0003-0131-5699)
- Mahmoud Nassar (ORCID: https://orcid.org/0000-0002-5401-9562)
- Omar S. Elsayed
- Mohammed A. Azab (ORCID: https://orcid.org/0000-0002-3519-9035)
- Adam Elswedy
- Ahmed Y. Azzam (ORCID: https://orcid.org/0000-0002-4256-0159)
- Mahmoud M Morsy (ORCID: https://orcid.org/0009-0001-4356-5306)
- Adham A. Mohamed
- Osman Elamin
Institutions
- St. Michael's Hospital (CA)
- National Institutes of Health (US)
- Albert Einstein College of Medicine (US)
- Cleveland Clinic (US)
- Montefiore Medical Center (US)
- Harvard University (US)
- University of Toronto (CA)
- Jordan Hospital (JO)
- Massachusetts General Hospital (US)
- National Institute of Neurological Disorders and Stroke (US)
- Jacobs Institute (US)
- Neurological Surgery (US)
- Cairo University hospitals (EG)
- October 6 University (EG)
- University at Buffalo, State University of New York (US)
- King Khalid University (SA)
Publication Details
- Journal
- ASIDE Internal Medicine
- Published
- 2024-11-27
- DOI
- https://doi.org/10.71079/2024001001
- Citations
- 1
- Primary Topic
- Cerebral Venous Sinus Thrombosis
- Type
- article
- Field-Weighted Citation Impact
- 0.37
Funders
- University at Buffalo
- National Center for Advancing Translational Sciences