Regenerative endodontic treatment for the management of immature permanent teeth with focal fibrous hyperplasia

Frequent irritation in the oral cavity can result in a benign condition called focal fibrous hyperplasia. This condition is rarely associated with an open apex in the teeth. This case report details the treatment of a patient with an open apex in teeth 11 and 12, worsened by localised fibrous hyperplasia. Regenerative endodontic therapy (RET) was employed for this patient. Remarkably, after initiating RET, the fibrous hyperplasia gradually resolved without the need for surgical excision. Following this observation, two hypotheses were proposed: (1) focal fibrous hyperplasia may have an endodontic origin and (2) hyperplastic development coupled with endodontic involvement might diminish with endodontic therapy alone. Excision of the growth is not always necessary. This case report highlights the potential connection between regenerative endodontic therapy and the resolution of focal fibrous hyperplasia, providing new insights into managing such rare conditions.