Frailty reduces penumbral volumes and attenuates treatment response in hyperacute ischemic stroke
Frailty is independently associated with reduced penumbra and poorer neurological recovery in acute stroke. These findings may explain the attenuated response to stroke reperfusion therapies seen in frailer individuals.
Authors
- Nicholas R. Evans (ORCID: https://orcid.org/0000-0002-7640-4701)
- Esmee Dohle (ORCID: https://orcid.org/0000-0002-5385-2026)
- Benjamin P. Lewis (ORCID: https://orcid.org/0000-0003-0491-3790)
- Smriti Agarwal (ORCID: https://orcid.org/0000-0001-5180-8809)
- Elizabeth A. Warburton (ORCID: https://orcid.org/0000-0003-2575-3255)
Institutions
- University of Cambridge (GB)
- Addenbrooke's Hospital (GB)
Publication Details
- Journal
- Age and Ageing
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1093/ageing/afae266
- Citations
- 6
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 2.07
Funders
- Stroke Association
- NIHR Cambridge Biomedical Research Centre