Self-Emulsifying Drug Delivery System (SEDDS) - An Overview

Self-Emulsifying Drug Delivery System (SEDDS) owns a promising future in enhancing solubility and bioavailability properties of sparingly water-soluble drugs.These are mixtures of drug, lipid, surfactants and oils.SEDDS are liquid to semisolid in nature, but it has some draw backs like formulation development, quality control, stability etc.To overcome this, liquid SEDDS can be converted into solid SEDDS such as pellets, tablets, capsules, microspheres, nanoparticles, microbeads, suppositories etc. without affecting drug release property.This article outlines the compilation of data on necessary aspects of self-emulsifying formulation such as excipients used, various dosage forms, novel ways to transform liquid SEDDS to solid SEDDS, it's applications and making way for further advancements in pharmaceutical investigation.