IMPACT OF COVID-19 ON DIAGNOSTIC ANALYSIS OF MYOCARDITIS

Introduction: Myocarditis is a disease caused by inflammation of the heart muscle, the myocardium. The myo-cardium is responsible for contracting and relaxing to pump blood in and out of the heart and the rest of the body. When this muscle becomes inflamed, its ability to pump blood becomes less effective. This causes prob-lems such as abnormal heartbeat, chest pain, or breathing disorders. In extreme cases, it can also cause blood clots that lead to heart attack, stroke, and even death. Purpose: To study the aggravating factors of COVID-19 that caused myocarditis and its prevention. Despite the distinctive clinical signs of patients with COVID-19, there are still elements that remain undiscovered, such as the prognostic factors of COVID-19, which include external factors, such as viral load and internal factors, which include the health conditions of the individual, the incidence rate of myocarditis and distinguishing signs. Materials and Methods: This is a retrospective study highlighting the clinical and radiographic signs of the above cases diagnosed with COVID-19. Demographic, epidemiologic, radiologic, and laboratory data collected from medical record reviews of adult patients diagnosed with COVID-19 provided the basis for their follow-up. Measurement of the cycle threshold value (Ct), real-time PCR (RT-PCR), electrocardiogram (ECG), and meas-urement of pulmonary inflammation index (PII) values were among the most frequent examinations performed in these patients. Results: In the study, 75 adult patients diagnosed with COVID-19 admitted to QSUNT were included, of which 15 cases were severe and 60 were in stable condition. The viral load of severe cases was significantly higher than that of stable patients, regardless of PCR values. Typical Ct abnormalities were more likely to exist in the severe group than in the non-severe group, associated with consolidation and thickening of the interlobular sep-tum and increased PII values. Of the 75 patients, 12 patients were noted to have an abnormal ECG and elevated serum myocardial enzyme levels, and five were clinically diagnosed with SARS-COV-2-induced myocarditis. Conclusion: During the patient study, three independent risk factors of COVID-19 were identified, which in-cluded age, PII, and Ct value. The Ct value is closely related to the severity of COVID-19 and may act as a pre-dictor of the clinical severity of early-stage COVID-19. Oxygen pressure, along with laboratory tests, are ele-ments that should not be neglected as they are also closely related to the severity of COVID-19.