CHA2DS2-VASc SCORE FOR PREDICTING THE RISK OF CONTRAST-INDUCED NEPHROPATHY AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT Transkateter Aort Kapak Replasmanı Sonrası Kontrasta Bağlı Nefropati Riskini Öngörmek için CHA2DS2-VASc Skoru

ABSTRACTObjective: Contrast induced nephropathy (CIN) is a condition that may develop due to percutaneous cardiacinterventional procedures and may adversely affect the prognosis of patients. The CHA2DS2-VASc scorehas been shown to be an independent predictor of acute kidney injury (AKI) and indicates an unfavorableprognosis in patients with acute coronary syndrome (ACS). Awareness of the risk of AKI before transaorticvalve replacement (TAVR) may help to reduce the rate of AKI. Therefore, i aimed to evaluate the utility ofCHA2DS2 VASC score in patients undergoing TAVR.Material and Methods: Retrospective date of 60 patients who underwent TAVR was collected betweenFebruary 2022 and October 2023. The decision for the TAVR procedure was made according to internationalguidelines and the consensus of the local cardiac team for patients with advanced aortic stenosis and highsurgical risk or contraindication to surgical valve replacement.Results: There were no significant differences between the two groups in terms of age, gender, prevalenceof diabetes mellitus, dyslipidemia, previous medications, baseline systolic and diastolic blood pressure,and body mass index. High CHA2DS2-VASc score (OR: 2.138, 95% confidence interval (CI): 1.356-4.125; p =0.027) levels were independently associated with the presence of CIN. Furthermore, contrast volume (OR:1.192, 95%CI: 1.022-1.390; p = 0.031) independently predicted the presence of CIN.Conclusion: This study demonstrated that the CHA2DS2-VASc score can be used as a predictor of CIN inpatients undergoing TAVR. Early prediction of CIN risk is critical to provide intensive preventive measures topatients at high risk. The CHA2DS2-VASc score is a simple and familiar scoring tool that can be applied in patientsundergoing TAVR and can predict the development of CIN and can be easily applied in daily practice.