Exploring the inhibitory potential of xanthohumol on MEK1/2: a molecular docking and dynamics simulation investigation
The findings of the study suggested that Xn, as a novel bioactive compound, potentially inhibits the MEK1/2 function in cancer cells.
Authors
- Mahmood Naderi (ORCID: https://orcid.org/0000-0003-4271-8910)
- Parviz Fallah (ORCID: https://orcid.org/0000-0002-1900-9959)
- Zohreh Gholizadeh Siahmazgi (ORCID: https://orcid.org/0000-0002-4813-7730)
- Shiva Irani (ORCID: https://orcid.org/0000-0002-4202-9931)
- Zahra Gohari
- Vahid Haghpanah (ORCID: https://orcid.org/0000-0001-8337-0602)
- Ali Ghiaseddin (ORCID: https://orcid.org/0000-0003-0168-8890)
- Hilda Samimi (ORCID: https://orcid.org/0000-0002-2009-0096)
- Amirreza Pashapour‐Yeganeh
- Fereshteh Soutodeh
- Jaber Afifeh
Institutions
- Tarbiat Modares University (IR)
- Islamic Azad University, Science and Research Branch (IR)
- Jahrom University of Medical Sciences (IR)
- Stem Cell Technology Research Center (IR)
- Alborz University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Research in Pharmaceutical Sciences
- Published
- 2024-11-01
- DOI
- https://doi.org/10.4103/rps.rps_38_24
- Primary Topic
- Hops Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00