Effects of Mental Disorders on Fibromyalgia Mediated by Insomnia: A Mendelian Randomization Study
This study showed a positive causal relationship between depression, irritability, insomnia, and fibromyalgia. Insomnia partly mediates this overall effect. Understanding the causal relationship between mental disorders and fibromyalgia and the mediating role of insomnia may provide more information for fibromyalgia intervention and prevention strategies.
Authors
- Le Chang (ORCID: https://orcid.org/0000-0002-5764-286X)
- Huang Canyang
- Shan Zeng (ORCID: https://orcid.org/0000-0002-0988-723X)
- Zhen Sun (ORCID: https://orcid.org/0000-0001-7430-8081)
- Zhenyu Cai (ORCID: https://orcid.org/0000-0003-0068-3238)
Institutions
- Fujian Medical University (CN)
- Quanzhou Normal University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/jpr.s491626
- Citations
- 3
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Fujian Medical University