Association of plasma branched-chain amino acid levels with colorectal cancer risk in a nested case–control study
We found no statistically significant inverse association between plasma BCAA concentrations and CRC risk in overall analyses, whereas on 6-year exclusion, total BCAA and leucine were associated with decreased CRC risk. Plasma BCAA concentrations may play a prophylactic role in colorectal carcinogenesis, and further investigation is warranted.
Authors
- Norie Sawada
- Shoichiro Tsugane (ORCID: https://orcid.org/0000-0003-4105-2774)
- Taiki Yamaji (ORCID: https://orcid.org/0000-0002-4799-8782)
- Manami Inoue
- Izumi Hisada (ORCID: https://orcid.org/0009-0008-9090-6434)
- Motoki Iwasaki
Institutions
- Jikei University School of Medicine (JP)
- National Cancer Research Institute (GB)
- International University of Health and Welfare (JP)
Publication Details
- Journal
- Japanese Journal of Clinical Oncology
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1093/jjco/hyae172
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- Japan Society for the Promotion of Science