P093 Associated risk factor of metabolic syndrome and relationship between metabolic syndrome and obstructive sleep apnea in Korean adults

Abstract Introduction Many studies have shown an association between metabolic syndrome (MetS), and obstructive sleep apnea (OSA). However, there are insufficient studies on whether STOP-BANG is associate with MetS in Korean adults. Therefore, we attempted to clarify this relationship in Koreans adults. Methods A total of 2,900 participants (1,233 men and 1,667 women) were enrolled in the Korean National Health and Nutrition Examination Survey from 2019 to 2020. We used the National Cholesterol Education Program Adult Treatment Panel III criteria for MetS and STOP-BANG questionnaire for OSA risk. Logistic regression analysis was used to measure the association between MetS and various confounding factors, including high OSA risk (STOP-BANG score≥3). Results The percentage of subjects with high OSA risk was significantly higher in subjects with MetS than without MetS (54.9% vs 27.7%; p<.001). In multivariate logistic regression analysis, high OSA risk (OR 1.490, 95% CI 1.139 to 1.948, p=0.004), men (OR 3.966, 95% CI 2.938 to 5.353, p<.001), waist circumference (OR 1.095, 95% CI 1.076 to 1.113, p<.001), fasting glucose (OR 1.038, 95% CI 1.028 to 1.047, p<.001), and systolic blood pressure (OR 1.038, 95% CI 1.030 to 1.047, p<.001) were significantly associated with MetS in Korean adults. Discussion These results suggest that there is a strong association between high OSA risk and MetS in Korean adults. Therefore, MetS evaluation is required in high OSA patients, and OSA diagnosis through PSG test and treatment is necessary.