Screening of novel lactic acid bacteria with high induction of immunoglobulin A production, dendritic cell activation, and interleukin-12 production
In this study, we screened 308 lactic acid bacteria strains for high immunoglobulin A (IgA) production, dendritic cell activation, and interleukin-12 (IL-12) production using human-derived cells. Among them, Lactobacillus helveticus GCL1815 demonstrated superior performance in all aspects, indicating its remarkable potential for immunomodulatory functions in both innate and adaptive immunity.
Authors
- Atsushi Yamatsu (ORCID: https://orcid.org/0000-0003-0452-8913)
- Keigo Tsuruno
- Yukimasa Tanaka-Azuma
- Takashi Mawatari
- Soichi Tanabe
Institutions
- Ezaki Glico (Japan) (JP)
Publication Details
- Journal
- Bioscience Biotechnology and Biochemistry
- Published
- 2024-12-13
- DOI
- https://doi.org/10.1093/bbb/zbae196
- Citations
- 4
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 1.39